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Pathmaker Neurosystems Announces Engagement of HERNETICS for Industrial Design

Boston, MA (June 10, 2015) – PathMaker Neurosystems Inc. (“PathMaker”), a clinical-stage neuromodulation company developing novel non-invasive systems for the treatment of neuromotor disorders, today announced that it is working with HERNETICS LLC for the design and development of first-in-class non-invasive devices based on trans-spinal direct current stimulation (tsDCS) technology that will be used for the treatment of patients with neuromotor disorders.

Trans-spinal direct current stimulation is a novel modality for non-invasive neuromodulation that has recently emerged, driven by fundamental new understandings of spinal circuit biology made by PathMaker’s scientific advisors. PathMaker expects its products to bring far-reaching changes in clinical practices for treating patients with neuromotor disorders. The Company’s tsDCS-based systems use weak subthreshold direct current to directly modulate spinal circuits in a non-invasive manner using skin surface electrodes. The Company is currently developing a family of products based on tsDCS that will open up new therapeutic options for patients with neuromotor disorders.

HERNETICS LLC, a Boston based product design consultancy, will lead the industrial design direction for PathMaker’s flagship products. HERNETICS will utilize Class II and Class III medical device experience to optimize the products’ ergonomics for operational safety while developing market appropriate aesthetics. HERNETICS’ engagement will assist Pathmaker in building the new tsDCS products for clinical trials, regulatory submission, and eventual commercial distribution.

“As we advance our product development plans, the award-winning industrial design expertise of HERNETICS will be brought to bear on the first-in-class non-invasive neuromodulation systems that we are building,” said Nader Yaghoubi, M.D., Ph.D., President and Chief Executive Officer of PathMaker Neurosystems.

PathMaker Neurosystems Inc. was founded to commercialize recent breakthrough advances in the development and clinical application of trans-spinal direct current stimulation (tsDCS) for patients with neuromotor disorders. tsDCS is a novel modality for non-invasive neuromodulation that has only emerged within the last five years, being driven by fundamentally new understandings of spinal circuit biology made by our Company’s scientific advisors and their clinical work in treating patients with paralysis, muscle weakness and muscle tone disorders. More than 27 million patients in the US and Europe suffer disabilities due to stroke, cerebral palsy, multiple sclerosis, spinal cord injury, traumatic brain injury, Parkinson’s disease and other neurological disorders, and the breakthrough non-invasive technology that PathMaker is developing promises to open up entirely new methods of treating these patients.

“By combining industrial design seamlessly with engineering and manufacturing, we hope to facilitate PathMaker’s effort to develop novel solutions for the challenge of neuromotor dysfunction,” said Hern Kim, Principal Designer at HERNETICS. “What PathMaker is doing with tsDCS is nothing short of extraordinary. We are delighted to be a part of the commercialization efforts as we strive to turn innovative ideas into successful products that improve patient quality of life.”

About PathMaker Neurosystems Inc.

PathMaker Neurosystems Inc. is a clinical-stage neuromodulation company founded to commercialize recent breakthrough advances in the development and clinical application of trans-spinal direct current stimulation (tsDCS) for patients with neuromotor disorders. More than 27 million patients in the US and Europe suffer disabilities due to stroke, cerebral palsy, multiple sclerosis, spinal cord injury, traumatic brain injury, Parkinson’s disease and other neurological disorders, and the breakthrough non-invasive technology that PathMaker is developing promises to open up entirely new methods of treating these patients.

Press Contact: Don Goncalves, Tiziani Whitmyre, 781.793.9380, dgoncalves@tizinc.com

About HERNETICS LLC

HERNETICS LLC is a privately managed award-winning product development consultancy specializing in rapid product design services for the consumer, industrial, and medical industries. The company was founded in 2007 based on the goal to provide the fastest product design phase in the industry for human-centered new product development. All of the services can be customized to target immediate client needs or be integrated into a holistic complete solution, with primary focus on speed to market. For more information please visit www.HERNETICS.com.